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Laugier hunziker syndrome

Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules 1-5 mm in size, frequently associated with longitudinal melanonychia. There is no underlying systemic abnormality or malignant predisposition associated with LHS, and therefore the prognosis. Laugier-Hunziker Syndrome. Laugier-Hunziker syndrome, also known as Laugier-Gerbig-Hunziker syndrome or Laugier-Hunziker-Baran syndrome or idiopathic lenticular mucocutaneous pigmentation, is a hereditary pigmentary disorder characterized by a unique expression of pigmentation over the mucosal, nail, and acral sites. The cond

Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. They appear as macular lesions less than 5 mm in diameter. Laugier-Hunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential LAUGIER-HUNZIKER SYNDROME. The Laugier-Hunziker syndrome is characterized by melanotic pigmentation of the mouth and lips which is frequently accompanied by longitudinal melanonychia. 5,540-543 In a small number of cases, there are dark palmoplantar and interdigital lesions. Pigmented macules may also develop about the nails Laugier-Hunziker syndrome (LHS) was initially described in 1970 as acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with longitudinal melanonychia... Laugier-Hunziker syndrome ( / ˈloʊʒieɪ ˈhʊntsɪkər /) is a cutaneous condition characterized by hyperpigmentation of the oral mucosa, longitudinal melanonychia, and genital melanosis. The hyperpigmentation presented in Laugier-Hunziker syndrome is benign and should be differentiated from Peutz-Jeghers syndrome Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by diffuse macular hyperpigmentation of the oral mucosa and, at times, longitudinal melanonychia. Although LHS is considered a benign disease with no systemic manifestations or malignant potential, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management

Laugier- Hunziker syndrome (LHS) is an uncommon and scarce syndrome associated with the conditions of hyperpigmentation of oral mucosa (membrane lining in the inner side of mouth) and also the pigmentations of nails. The pigmentations are likely to be dark brown biconvex discoloration located majorly on the mucosa and beneath the lips, whereas the. Laugier-Hunziker syndrome is a rare acquired macular hyperpigmentation of oral mucosa and lips frequently associated with longitudinal pigmentation of the nails . The pathogenesis is unknown, but no systemic involvement or malignant predisposition has been described, so the correct clinical identification avoids the need for detailed and potentially hazardous investigations and treatment [ 3 ] Laugier Hunziker syndrome is a rare disorder that is characterized by adult-onset hyperpigmented macules of the lips, oral cavity, and fingertips. Longitudinal melanonychia is present in the majority of cases. We present a 45-year-old woman with adult-onset hyperpigmented macules of the oral cavity as well as linear melanonychia that involved.

Laugier-Hunziker Syndrome: A Rare Cause of Oral and Acral

Anaemia with Laugier-Hunziker Syndrome: a diagnosticLaugier-Hunziker syndrome

Laugier-Hunziker syndrome is a harmless rare sporadic disorder that is characterised by flat brown marks on the lips and inside the mouth and frequently brown stripes on the nails. The soft Dura-Foam insole with enhanced arch support provides all-day comfort. Ames IA 50010 515-233-4450 Ankeny Area 1520 NW Irvinedale Dr Laugier-Hunziker syndrome (LHS) is a rare, idiopathic pigmentary disorder especially affecting the lips and oral mucosa. At present, no more than 200 cases of patients diagnosed with LHS syndrome have been described worldwide. To date, three patients under the age of 20 have been described, including the youngest patient who is a 12-year-old child

Laugier-Hunziker syndrome is a sporadic condition characterised by essential acquired and benign melanotic pigmentation of the oral cavity and lips which is often associated with spotted macular pigmentation of the fingertips and longitudinal melanonychia. 2 Since its first description by Laugier and Hunziker in 1970, 10 more than 100 cases have been described world wide. The basic skin lesions manifest as irregular lenticular hyperpigmented macules of 2-5 mm diameter which can be slate to. The Laugier-Hunziker syndrome (LHS) is a rare benign condition, characterized by acquired pigmentation of the nails and melanotic pigmentation of the parts of the oral cavity such as lips, buccal, and palatal mucosa, [ 1 ]. Oral pigmentation is either focal or diffuse

Laugier-Hunziker Syndrome - PubMe

  1. Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary disease of oral cavity and lips along with longitudinal melanonychia. We hereby report a case of a young female with multiple melanotic macules over the tongue and palms, along with multiple streaks of longitudinal melanonychia
  2. Laugier-Hunziker syndrome (LHS) is a rare, acquired, disorder of pigmentation characterized by hyperpigmentation of lips, oral mucosa, and longitudinal melanonychia. The disease is a diagnosis of exclusion and is diagnosed mainly on the basis of clinical and histopathological features
  3. Résumé - La mélanose essentielle ou syndrome de Laugier-Hunziker représente un trouble de la pigmentation rare et acquis, d'étiologie inconnue, qui touche surtout les femmes caucasiennes d'âge moyen

Laugier-Hunziker syndrom

Laugier-Hunziker syndrome (LHS) is an infrequent disorder, characterized by brown macular hyperpigmentation as a grayish brown lentiginous macules of about 5 mm, of the lips and oral mucosa. It is a benign entity without systemic manifestations Laugier-Hunziker syndrome is a rare disease. There are currently no additional known synonyms for this rare genetic disease. This muco-cutaneous hyperpigmentation syndrome might be confused with Peutz-Jeghers syndrome. It differs in that in Peutz-Jeghers the lesions occur at at an early age. The lesions in Laugier.

Laugier-Hunziker syndrome, also known as Laugier-Gerbig-Hunziker syndrome or Laugier-Hunziker-Baran syndrome or idiopathic lenticular mucocutaneous pigmentation, is a hereditary pigmentary disorder characterized by a unique expression of pigmentation over the mucosal, nail, and acral sites. It is commonly mistaken for Addison's disease, Peutz. Laugier-Hunziker syndrome (LHS) comprises benign mucosal pigmentation in the absence of gastroin-testinal pathology. • Differentiating LHS from Peutz-Jeghers syndrome can prevent unnecessary aggressive cancer screening protocols. • The average age of onset of LHS is 52 years an Veraldi S, Cavicchini S, Benelli C, Gasparini G (1001) Laugier-Hunziker syndrome: a clinical, histopathologic, and ultrastructural study of four cases and review of the literature. Journal of the American Academy of Dermatology 25(4): 632-636 CrossRef Google Schola

Mucocutaneous hyperpigmentation alone is not uncommon in Asian, black and other dark-skinned people.1 Laugier-Hunziker syndrome, however, is an acquired pigmentary disorder of the lips, oral mucosa and fingers, and is known to be an entirely benign disease with no systemic manifestations. Although rarely reported in the literature, its incidence is unknown Laugier-Hunziker syndrome (LHS) is a rare mucocutaneous disorder, of unknown etiology, characterized by multiple hyperpigmented macules, dispersed mostly on the oral mucosa, occasionally associated with longitudinal ridging of the nails. The diagnosis requires exclusion of other conditions, such as Addison's disease and Peutz-Jeghers syndrome Laugier-Hunziker syndrome is one of those rare syndromes which has yet not been reviewed and reported much in literature. So far, there is no diagnostic criteria and classification that can help with prompt diagnosis of this syndrome. In this article an attempt has been made to put forwar Peutz-Jeghers syndrome shares some dermatological features with Laugier-Hunziker syndrome. 3 Laugier-Hunziker syndrome is a rare sporadic disorder which is characterized by acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with macular pigmentation of the fingertips and longitudinal melanonychia. 4. The Laugier-Hunziker syndrome. East Afr Med J, 2004, 81(10): 544-545. 编辑: 费杨虹虹 版权声明. 本网站所有注明来源:丁香园的文字、图片和音视频资料,版权均属于丁香园所有,非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源:丁香园。.

Laugier Hunziker Syndrome - an overview ScienceDirect Topic

Laugier-Hunziker syndrome (LHS) is a rare, acquired pigmentary condition of the lips, buccal mucosa, and fingers. It was firstly described in 1970 by Laugier and Hunziker [].Since then, patients with this syndrome have mainly been studied by researchers of Western Europe and Japan [6, 11, 17].These lesions of the lips and mucosa present as multiple, flat, smooth, discrete or confluent. Laugier-Hunziker syndrome (LHS) is a rare, acquired disorder characterized by benign macular hyperpigmentation of the oral and genital mucosa, which is associated with longitudinal melanonychia in 50% to 60% of cases. 1 Dermoscopic examination should be indicated for patients with LHS who have several pigmented lesions on the mucosa, nails, or. Laugier-Hunziker Syndrome D. Fisher Oral Medicine Unit, Liverpool University Dental Hospital, Pembroke Place, Liverpool, L3 5PS and Dermatology Department, Clatterbridge Hospital, Clatterbridge Road, Bebington, Wirral, CH63 4JY, U The Laugier-Hunziker syndrome--a clinical review of six cases. Clin Exp Dermatol. 1990; 15: 111-4. 6. Lampe AK, Hampton PJ, Woodford-Richens K, et al. Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome. J Med Genet. 2003; 40: e77. 7. Eisen D. Disorders of pigmentation in the oral cavity. Clin Dermatol.

Laugier-Hunziker Syndrome: Background, Pathophysiology

Laugier-Hunziker syndrome (LHS), a rare, acquired pigmentary disorder of the lips, oral mucosa, and fingers, is known to be an entirely benign disease with no systemic manifestations. In the past. The first case of the Laugier-Hunziker syndrome in Scandinavia is reported and other conditions causing diffuse or multifocal pigmented oral lesions are discussed. Expand. 27. View 1 excerpt, references background; Save. Alert. Additional conjunctival and penile pigmentation in Laugier-Hunziker syndrome: a report of two cases Keywords: Laugier-Hunziker syndrome; Q-switched Nd-Yag laser 1. Case report finger showed basal hyper-pigmentation, better visible after staining with Masson-Fontana, and few A 46-year-old Caucasian woman presented with a melanophages in the papillary dermis. A biopsy of the 20-year history of macular pigmentation on the buccal elbow lesion. Background: Laugier-Hunziker syndrome (LHS) is a rare sporadic disorder, characterized by acquired macular hyperpigmentation of the oral and genital mucosa, often associated with longitudinal melanonychia. No underlying systemic abnormalities are associated with LHS and no malignant predisposition exists. Cases have been reported in related family members

Laugier P, Hunziker N (1970) Essential lenticular melanic pigmentation of the lip and cheek mucosa. Arch Belg Dermatol Syphiligr 26: 391-399; Lenane P et al. (2001) The Laugier-Hunziker syndrome. J Eur Acad Dermatol Venereol 15: 574-577; Makhoul EN et al. (2003) Familial Laugier-Hunziker syndrome. J Am Acad Dermatol 49: S143-14 Laugier-Hunziker syndrome . Title. We are currently developing a new version of GARD. This site is in-development and may not reflect the final version. Preview the new GARD site. Other Names: LHS; Laugier and Hunziker pigmentation. Do you have updated information on this disease? We want to hear from you The Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal melanonychia. It is a diagnosis of exclusion, and other systemic conditions should be excluded prior to making a diagnosis. From the original description to date, around 200 cases have been reported. Laugier-Hunziker Syndrome is a benign condition that is harmless and creates hyperpigmentation of the oral mucosa and outside of the lips. It can be caused b..

Laugier-Hunziker lesions to oral cancer, and therefore all cases must be simply followedup without any specific treatment [11]. However a diagnosis of Laugier-Hunziker syndrome must be established to exclude underlying sys-temic pathologic conditions. Addison's disease is an endocrine disorder due to a

Laugier-Hunziker syndrome - Wikipedi

  1. Laugier-Hunziker Syndrome. This rare skin disorder causes flat, brown spots on the lips and the mouth's mucous membranes. The reason for this condition is still unknown, but it doesn't appear to.
  2. Laugier-Hunziker syndrome is characterized by the presence of a variable number of asymptomatic, discrete, slate to brown-black pigmented macules involving the oral mucosa and lips, which are sometimes confluent or even diffuse 3, 4, 5.Buccal mucosa is commonly affected and reports also include pigmentation of the hard and soft palate, the gingival, the palatoglossal arch, the floor of the.
  3. Laugier-Hunziker syndrome (LHS), on the other hand, is an acquired benign disorder having similar dermatological picture but no systemic manifestations(2). We herein describe a child with classical LHS to underline the importance of this differential diagnosis. The patient also had longitudinal melanonychia, a hitherto unreported finding in.

Core tip: Although Laugier-Hunziker syndrome (LHS) is an uncommon disorder, labial or oral pigmentation is often encountered daily and clinically. By conducting a thorough review of the topic, the aims of the paper are to present the clinical, dermoscopic, and pathological features of LHS concisely and clearly The patient was diagnosed to have a Laugier-Hunziker-Baran syndrome. Einleitung Es soll ein weniger bekanntes dermatologisches Krankheitsbild, das Laugier- Hunziker-Baran-Syndrom vorgestellt beziehungsweise wieder in das Gedächtnis gerufen werden, da die Hyperpigmentierungen, die im Rahmen dieser Dermatose auftreten, den Patienten oft. Laugier-Hunziker syndrome is an acquired benign disorder presenting in adults with lentigines on the lips and buccal mucosa. It frequently is accompaniedby longitudinal melanonychia, macular pigmentation of the genitals, and involvement of the palms and soles Laugier-Hunziker syndrome is a benign chronic progressive asymptomatic hyperpigmented macules on the lips and buccal mucosa and often is associated with longitudinal melanonychia (A). The main differential diagnoses are drug induced hyperpigmentation, racial pigmentation, smoker s melanosis, Addisons disease and Peutz-Jeghers syndrome (B)

Laugier-Hunziker syndrome: A case report and review of the

Laugier-Hunziker syndrome is an extremely rare disorder but is of some interest to dental practitioners. The importance of the condition relates to it being included in the differential diagnosis. Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker. In 1970, Laugier and Hunziker 1 reported five cases of essential melanotic pigmentation of the mouth and the lips. Two of these patients also displayed pigmentary changes in the nails. Sartoris et al 2 reported two cases with a nail anomaly in one, and in 1977, Laugier et al 3 also described another patient with pigmented nails. We have encountered Laugier-Hunziker syndrome in nine patients. Laugier-Hunziker syndrome is a benign skin condition that causes dark brown spots, called macules, on the lips and the lining of the mouth. Macules can be 2-5 millimeters in diameter and also.

Laugier-Hunziker syndrome is characterized by the combination of oral mucosal hyperpigmentation and melanonychia in 50% to 60% of cases. 1. Sachdeva S. Sachdeva S. Kapoor P. Laugier-hunziker syndrome: a rare cause of oral and acral pigmentation LEOPARD Syndrome; NAME syndrome (identical to LAMB syndrome, Carney syndrome, Carney complex) Tay-Sachs syndrome (seesphingolipidoses below, detection of café-au-lait stains) Localized lentiginosis. Bandler Syndrome; Peutz-Jeghers Syndrome; Lentiginosis centrofacialis (Touraine) Laugier-Hunziker syndrome

Laugier Hunziker syndrome Pictures, Symptoms, Causes

Laugier-Hunziker syndrome is a benign mucocutaneous pigmentary disorder that mainly affects the oral mucosa and nails. A series of six cases is presented, including two patients from the same family. A review of the literature is performed, as well as a discussion on its differential diagnosis from other relevant local and systemic pigmentary. Laugier-Hunziker Syndrome Laugier-Hunziker Syndrome Fisher, D.; Field, E. A.; Welsh, S. 2004-05-01 00:00:00 Laugier-Hunziker Syndrome (LHS) is a benign macular hyperpigmentation of the lips and oral mucous membranes, with pigmentation of the nails in a longitudinal banding pattern. We report a 28‐year‐old woman who was referred by her dentist with a 5‐month history of brown. The differential diagnosis should include Laugier-Hunziker syndrome and Peutz-Jeghers syndrome.The absence of systemic features and involvement at other sites should assist in differentiating oral. She has been married to Tomaso Trussardi since October 10 2014. The most Hunziker families were found in the USA in 1920.. Listen to the audio pronunciation of Laugier-Hunziker syndrome on pronouncekiwi. Sign in to disable ALL ads. Thank you for helping build the largest language community on the internet. pronouncekiwi - How To Pronounce Laugier-Hunziker.

Laugier-Hunziker Syndrome: An Uncommon Cause of Oral

Abstract Laugier-Hunziker syndrome (LHS) is an acquired disorder characterized by pigmentation of oral tissues and nails. We present a case of LHS in an 89-year-old male that was seen at the college of dentistry when the patient presented for routine dental care Laugier-Hunziker syndrome is a sporadic condition charac-terised by essential acquired and benign melanotic pigmenta-tion of the oral cavity and lips which is often associated with spotted macular pigmentation of the fingertips and longitudi-nal melanonychia.2 Since its first description by Laugier an Laugier-Hunziker syndrome (LHS), also known as idiopathic lenticular mucocutaneous pigmentation, is a rare, benign condition, characterized by acquired hyperpigmented macules in otherwise asymptomatic, adult patients

Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. They appear as macular lesions less than 5 mm in diameter. It's considered to be a benig Laugier-Hunziker syndrome was made. In fol-low-up over the next five years, an increasing number of pigmented macules was noted. Mucocutaneous hyperpigmentation alone is not uncommon in Asian, black and other dark-skinned people.1 Laugier-Hunziker syndrome, however, is an acquired pigmentary disorder of the lips, oral mucosa and fingers. Laugier- Hunziker syndrome (LHS) is a rare benign acquired disorder that is characterized by hyperpigmented macules of the oral cavity, lips and tips of the fingers and toes, often associated with longitudinal melanonychia. The case discussed here is a 50-year-old woman with clinical and histopathological features suggestive of LHS laugier hunziker syndrome - this is an unpleasant disease. The photos of laugier hunziker syndrome below are not recommended for people with a weak psyche! We wish you a cure and never get sick of this disease! Поделиться на Facebook Symptomps. fatty tissue. Symptomps This case may be Laugier-Hunziker syndrome. It is an acquired condition with striking macular pigmentation of the oral cavity presenting most commonly on the lips followed by the hard palate, buccal mucosa, soft palate, tongue and gingiva (9). The macules are dark brown with irregular shapes and shades of brown pigmentation, which was the case.

Laugier Hunziker syndrome - eScholarshi

These dermatological features can also be observed in the Laugier-Hunziker syndrome, usually a sporadic but sometimes familial condition not associated with increased cancer risk[41,42]. In this syndrome, a spotty pigmentiation of the nails may be observed as well. Interestingly, peritoneal pigmentation ahs been reported as well[52] Laugier-Hunziker syndrome is an acquired benign disorder presenting in adults with lentigines on the . lips and buccal mucosa. It frequently is accompanied by longitudinal melanonychia, macular pigmentation of the genitals, and involvement of the palms and soles. The diagnosis of Laugier-Hunziker syndrome i Laugier-Hunziker syndrome (LHS) is a rare, acquired mucocutaneous hyperpigmentation often associated with longitudinal melanonychia. It is important to differentiate this condition from the pigmentary disorders of the oral mucosa. The correct clinica The Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal melanonychia. It is a diagnosis of exclusion, and other systemic conditions should be excluded prior to making a diagnosis. Normally, no treatment is required for this condition, unless for aestheti

Laugier-Hunziker syndrome: a report of three cases and

  1. Laugier-Hunziker syndrome is an acquired disease, characterized by mucocutaneous hyperpigmentations, which was first described by Hunziker and Laugier in 1970 . There are approximately 200 reported cases in the literature. The average age of the reported cases at diagnosis is 47.5 years old (range 12-87 years)
  2. Laugier-Hunziker syndrome (/ ˈ l oʊ ʒ i eɪ ˈ h ʊ n t s ɪ k ər /) is a cutaneous condition characterized by hyperpigmentation of the oral mucosa, longitudinal melanonychia, and genital melanosis. The hyperpigmentation presented in Laugier-Hunziker syndrome is benign and should be differentiated from Peutz-Jeghers syndrome
  3. Maladie de Laugier. Signes de la maladie de Laugier. Hypermélaninose basale avec incontinence du pigment sur les muqueuses buccale et génitale. Lentigines de la lèvre inférieure, du palais osseux, parfois des doigts et des ongles. Examens complémentaires diagnostiques
Refractory Pigmentation Associated with Laugier-HunzikerLaugier–Hunziker syndrome in a young female Verma B, Behra

Laugier-Hunziker syndrome - Indian Journal of Dermatology

The Laugier-Hunziker syndrome is an acquired, idiopathic and benign mucocutaneous hypermelanosis that usually occurs on the lips and oral mucosa. Nail are frequently involved, mainly forming longitudinal hyperpigmented lines. A case of a 50 ye Laugier-Hunziker syndrome. Share. Medical conditions similar to or like Laugier-Hunziker syndrome. Cutaneous condition characterized by hyperpigmentation of the oral mucosa, longitudinal melanonychia, and genital melanosis Laugier-Hunziker syndrome. Laugier-Hunziker syndrome typically occurs during adulthood, and its exact etiology remains unknown. To date, evidence supporting an increased risk of malignancy is lack-ing. This syndrome occurs predominantly in middle-aged women.1 It is characterized by mucocutaneous pigmentator Laugier-Hunziker syndrome in a patient with Sjögren's syndrome. Report of one case Laugier-Hunziker syndrome is a rare benign idiopathic condition charac-terized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is t Laugier-Hunziker syndrome (LHS) is a rare, acquired disorder characterized by a varying number of asymptomatic, lenticular or linear, brown to black mucocutaneous macules. The hyperpigmentation occurs spontaneously in the adulthood and is considered permanent. Pathophysiology of this syndrome is still unknown

Laugier-Hunziker Syndrome Clinical Presentation: Physical

Laugier-Hunziker Syndrome (LHS) was first recognized in the year 1970, and was depicted as acquired hyperpigmented macules of the lips and buccal mucosa mostly linked with longitudinal melanonychia of the nails. A rare benign condition, the syndrome is apparently characterized by macular pigmentation of the genitalia but not Laugier-Hunziker syndrome. Contrarily, lentigines are a well-recognized complication of PUVA therapy.5 D. No treatment necessary e Correct. Laugier-Hunziker syndrome is a benign condition that does not require treatment other than for cosmetic reasons. Cosmetic treatment modalities that have been suc

Laugier–Hunziker syndrome: case report and review of theMelanocytic nevi | Basicmedical KeyMultiple, painless brown-black pigmentation, on the buccalDermoscopic Examination of Nail Pigmentation | Dermatology

Laugier and Hunziker described a syndrome consisting of asymptomatic benign areas of hyperpigmentation affecting the lips, buccal mucosa and, in 50%, the fingernails. We report a 67-year-old woman with the clinical features of Laugier-Hunziker syndrome in association with vulval pigmentation. Histology, immunohistochemistry and electron microscopy from the various areas of pigmentation on the. Laugier-Hunziker syndrome. This is a benign skin condition that involves the oral cavity, mainly the lower lip. It causes brown or black macules on the lips that can range from 1 to 5 millimeters. Laugier-Hunziker syndrome (/ ˈ l oʊ ʒ i eɪ ˈ h ʊ n t s ɪ k ər /) is a cutaneous condition characterized by hyperpigmentation of the oral mucosa, longitudinal melanonychia, and genital melanosis. The hyperpigmentation presented in Laugier-Hunziker syndrome is benign and should be differentiated from Peutz-Jeghers syndrome. See als The Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal melanonychia. It is a diagnosis of exclusion, and other systemic conditions should be exclude Laugier-Hunziker syndrome, also known as Lau-gier-Hunziker-Baransyndrome,Laugier-Gerbig-Hunziker syndrome, or idiopathic lenticular mucocutaneous pig-mentation, is a rare, acquired disorder characterized by mucocutaneous hyperpigmentation and melanonychia striata with no underlying systemic abnormalities [1].